A Cluster Reduction for Computing the Subtree Distance between Phylogenies
نویسنده
چکیده
Calculating the rooted subtree prune and regraft (rSPR) distance between two rooted binary phylogenetic trees is a frequently applied process in various areas of molecular evolution. However, computing this distance is an NP-hard problem and practical algorithms for computing it exactly are rare. In this paper, a divide-and-conquer approach to calculating the rSPR distance is established. This approach breaks the problem instance into a number of smaller and more tractable subproblems. Two reduction rules which were previously used to show that computing the rSPR distance is fixed-parameter tractable can easily be used to complement this new theoretical result, and so a significant positive impact on the running time of calculating this distance in practice is likely.
منابع مشابه
On the Linear-cost Subtree-transfer Distance between Phylogenetic Trees (revised Version of Dimacs Technical Report 97-18) 1
Di erent phylogenetic trees for the same group of species are often produced either by procedures that use diverse optimality criteria [16] or from di erent genes [12] in the study of molecular evolution. Comparing these trees to nd their similarities and dissimilarities (i.e. distance) is thus an important issue in computational molecular biology. Several distance metrics including the nearest...
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